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6,11-dihydro-11-ethyl-6-methyl-9-nitro-5H-pyrido[2,3-b][1,5]benzodiazepin-5-one

Development stage: Preclinical
Modality: Small Molecules

Overview

This compound is a synthetic small molecule belonging to the class of alkyldiarylamines and structurally classified as a pyridobenzodiazepine derivative. It has been studied primarily as an experimental antiviral agent targeting HIV. The mechanism of action is believed to involve inhibition of HIV reverse transcriptase by binding to the non-nucleoside inhibitor binding pocket (NNIBP), thereby blocking viral replication. It is not approved for clinical use and remains an experimental compound[1][2][8].

Other names: N11-Ethyl-N6-methyl-9-nitro-6,11-dihydro-5H-pyrido(2,3-b)(1,5)benzodiazepin-5-one132687–06–0

Targets

Human immunodeficiency virus type 1 reverse transcriptase

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